This category links to companies actively involved in research and development of their potential therapeutic products, derived from biological rather than chemical synthesis.
A privately held company that specializes in research for treatment of cancer, diabetes, multiple sclerosis, HIV/AIDS and infectious diseases, including Lyme Disease. Lists research projects and procedures. Based in San Diego, California. www.mixturesciences.com
Develops products using vaccine-like technology for neutralizing hormones which participate in gastrointestinal system and reproductive system cancer and non-cancer diseases and the prevention of pregnancy. Based in Miami, Florida. (Nasdaq: APHT) www.aphton.com
Company developing therapeutics of aptamers, for the prevention and treatment of chronic and acute disease. Includes overview of technology and commercial potential, careers and contacts in Cambridge, Massachusetts. www.archemix.com
Receptor-based drug discovery in the fields of diabetes, obesity, cardiovascular, sleep disorders, neurodegeneration, schizophrenia, depression and anxiety. Comprehensive profile of company in San Diego, California. (Nasdaq: ARNA) www.arenapharm.com
Developing diagnostics and drugs from core discoveries in protein and polysaccharide chemistry, including anti-viral attachment inhibitors. Includes research overview, distributors, and offices in Chicago and Santa Monica, California. www.ausambiotech.com
Develops and commercializes a vaccine against human chorionic gonadotropin secreting cancers, and synthetic antisense technology to inhibit translation in treating cardiovascular, kidney and viral diseases. Research and manufacturing facilities in Corval www.antivirals.com
Develops gene-based therapeutic products derived from adeno-associated virus for the treatment of inherited and acquired diseases. Includes explanation of technology, product pipeline, collaborative partnerships and investment data, from manufacturing fac www.avigen.com
Researches and develops biopharmaceutical products which address the role of blood and blood vessels in the prevention and treatment of diseases by inhibiting growth or enhancing bioavailability of drugs. Based in Rockville, Maryland. (Nasdaq: ENMD) www.entremed.com
Innovating viral phospholipase inhibitor to prevent expression of Herpes specific genes, and intracellular viral antigens, and drug inducing death of tumor cells and autoreactive immune cells, in multiple sclerosis, rheumatism, and Crohn's disease. Based www.biosphings.com
Company focusing on G-protein coupled receptor signaling as targets for therapeutic products. Includes corporate data, partnering and technology overviews, with media resources, list of publications, and opportunities in Chicago, Illinois. www.cuebiotech.com
Developing small molecule and peptide drugs in regulatory signaling and regenerative pathways. Introduces technical background, product pipeline, collaborations, investment data and careers headquartered from Cambridge, Massachusetts. (Nasdaq: CVGP) www.curis.com
Engaged in the identification, validation and selection of novel drugable targets and product candidates for the diagnosis and treatment of chronic inflammatory diseases. Profiles of technology, product pipeline and corporation in Labege, France. www.endocube.fr
Discovers, develops and commercializes therapies for systemic lupus erythematosus, viral diseases and cancer. Located in Redwood City, California.(Nasdaq: GNLB) www.genelabs.com
Genetic engineering techniques in the discovery, development, production, and marketing of human therapeutics. Includes research history, product pipline, global corporate and career information, from South San Francisco, California. www.gene.com
Researching nuclear receptors and gene deregulation for treatment of cardiovascular, metabolic and inflammatory diseases. Includes information about genomic research headquartered in Loos, France. www.genfit.com
Engaged in the discovery and development of novel therapeutics and diagnostics using synthetic DNA and antisense technology. Based in Cambridge, Massachusetts. (AMEX: HBY) www.hybridon.com
Researches and develops growth factor blockers and anti-cancer vaccines. Includes clinical programs, investor details and overview of company in New York City. (Nasdaq: IMCL) www.imclone.com
Develops antibacterial and antifungal drugs, including protegrins and related antimicrobial peptides, for application in cystic fibrosis. Includes pipeline, publications, and investor information from Palo Alto, California. (Nasdaq: IBPI) www.intrabiotics.com
Developing novel drugs against targets inside nerve cells to treat CNS disorders. Includes therapeutic projects, target biochemistry, corporate data and contacts for headquarters in New York City. www.intracellulartherapies.com
Develops proprietary protein modifications including PEG, glycosylation and vaccines. Overview of technologies, clinical trial pipeline, investor data and careers in Redwood City, California. (Nasdaq: MAXY) www.maxygen.com
Specialist in the design, development, and marketing of human cell replacement therapy systems, targeting inflammatory disease. Includes directions to research labs at Ann Arbor, Michigan, and corporate offices in Lincoln, Rhode Island. www.nephrostherapeutics.com
Drug discovery and development company using pathway engineering and chemistry to optimise the activity of natural products for the treatment of infectious diseases. Introduces biotransformation technology, lead compounds, key personnel in Hatfield, Engla www.novactabio.com
Researches and develops neurological diagnostics and pharmaceuticals for the aging population with emphasis on Alzheimer's disease. Profile of company with bases in Maywood, New Jersey and Saint Laurent, Quebec. (Nasdaq: NYMX) www.nymox.com
Structure-based drug design start-up, specializing in the ribosome as a target, and bacterial antibiotic resistance. Includes mechanisms of action, glossary, careers, corporate news and contacts and directions in New Haven, Connecticut. www.rib-x.com