Sites about the defense mechanism of the body which are dependent on the humoral aspects of immunity
as compared to the cell-mediated aspects which secrete Cytokines.
Sites may include the mechanisms of interaction of antibody with antigen, as well as the cascade sequence that this invokes, through the complement system.Sites may describe the molecular structure of antibodies, their classification and problems associated with their synthesis, such as the glycosylation of recombinant
proteins, to mimic mammalian species, but are produced in plant cell host, "Plantibodies".
Resources describing the process of creating humanized antibodies, their uses and their history. Maintained by Birkbeck College, London, UK. www.cryst.bbk.ac.uk/~ubcg07s
Attempts to summarize useful information on antibody structure and sequence. Provides a query interface to the Kabat antibody sequence data, general information on antibodies and crystal structures, and links. www.bioinf.org.uk/abs
Molecular images, history of monoclonal antibodies, activity related to sequence, and humanisation for therapy. Includes information on the maintainer and his research group at Cambridge, UK. www.path.cam.ac.uk/~mrc7/mikeimages.html
Interface to introduce the various immunoassays in current use, production and purification methods, labeling and assay development, from a manufacturer, with worldwide distribution in Pierce Biotechnology, Inc., Rockford, IL. www.piercenet.com/products/browse.cfm?fldID=0101
Database of immunoglobulins, monoclonals and whole sera, to nucleic acids and markers, with host and antigen species, clone and isotype id, and distribution details. Includes online demo with CD available for purchase from Key West, Florida. www.antibodies-probes.com
Article on the history of vaccination, the role of the humoral response in organ and bone marrow transplantation, leukaemia and lymphoma, and rheumatoid disease. Includes links to laboratories at the Therapeutic Antibody Centre, Oxford, UK. www.molbiol.ox.ac.uk/pathology/tig/new1/mabth.html
Laboratory concentrating on protein engineering and directed molecular evolution, especially of immunoglobulins. Includes PDFs of molecular structures, publications since 1985, and contacts at the University of Zurich in Switzerland. www.biochem.unizh.ch/plueckthun
Database for searching and browsing commercial, academic and therapeutical monoclonal antibodies through gene name, accession number, taxonomy, ontology, disease, and amino acid sequences. www.exactantigen.com
Forsiden | 